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KMID : 1164220050170020125
Journal of Korean Society for Radiotherapeutic Technology
2005 Volume.17 No. 2 p.125 ~ p.131
Effectiveness of the Respiratory Gating System for Stereotectic Radiosurgery of Lung Cancer
Song Heung-Kwon

Yang Oh-Nam
Kwon Kyung-Tae
Park Cheol-Su
Kim Min-Su
Kim Jeong-Man
Abstract
Purpose : For stereotactic radiosurgery (SRS) of a tumor in the region whose movement due to respiration is significant, like Lung lower lobe, the gated therapy, which delivers radiation dose to the selected respiratory phases when tumor motion is small, was performed using the Respiratory gating system and its clinical effectiveness was evaluated.

Materials and Methods : For two SRS patients with a tumor in Lung lower lobe, a marker block (infrared reflector) was attached on the abdomen. While patient¡¯ respiratory cycle was monitored with Real-time Position Management (RPM, Varian, USA), 4D CT was performed (10 phases per a cycle). Phases in which tumor motion did not change rapidly were decided as treatment phases. The treatment volume was contoured on the CT images for selected treatment phases using maximum intensity projection (MIP) method. In order to verify setup reproducibility and positional variation, 4D CT was repeated.

Results : Gross tumor volume (GTV) showed maximum movement in superior-inferior direction. For patient #1, motion of GTV was reduced to 2.6 mm in treatment phases (), while that was 9.4 mm in full phases () and for patient #2, it was reduced to 2.3 mm in treatment phases (), while it was 11.7 mm in full phases (). When comparing two sets of CT images, setup errors in all the directions were within 3 mm.

Conclusion : Since tumor motion was reduced less than 5 mm, the Respiratory gating system for SRS of Lung lower lobe is useful.
KEYWORD
stereotactic radiosurgery, respiratory cycle, respiratory gating system
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